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Deoxyguanosine is a TLR7 agonist
Toll‐like receptor 7 (TLR7) is an innate immune sensor for single‐strand RNA (ssRNA). Recent structural analysis revealed that TLR7 has an additional binding site for nucleosides such as guanosine, and is activated when both guanosine and ssRNA bind. The nucleoside binding site also accommodates imi...
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| Publicado no: | Eur J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6972671/ https://ncbi.nlm.nih.gov/pubmed/31608988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948151 |
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