Vitamin D differentially regulates colon stem cells in patient‐derived normal and tumor organoids

Intestine is a major target of vitamin D and several studies indicate an association between vitamin D deficiency and inflammatory bowel diseases (IBD), but also increased colorectal cancer (CRC) risk and mortality. However, the putative effects of 1α,25‐dihydroxyvitamin D(3) (calcitriol), the activ...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:FEBS J
Main Authors: Fernández‐Barral, Asunción, Costales‐Carrera, Alba, Buira, Sandra P., Jung, Peter, Ferrer‐Mayorga, Gemma, Larriba, María Jesús, Bustamante‐Madrid, Pilar, Domínguez, Orlando, Real, Francisco X., Guerra‐Pastrián, Laura, Lafarga, Miguel, García‐Olmo, Damián, Cantero, Ramón, Del Peso, Luis, Batlle, Eduard, Rojo, Federico, Muñoz, Alberto, Barbáchano, Antonio
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Editor's Choice
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972655/
https://ncbi.nlm.nih.gov/pubmed/31306552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14998
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