Vitamin D differentially regulates colon stem cells in patient‐derived normal and tumor organoids

Intestine is a major target of vitamin D and several studies indicate an association between vitamin D deficiency and inflammatory bowel diseases (IBD), but also increased colorectal cancer (CRC) risk and mortality. However, the putative effects of 1α,25‐dihydroxyvitamin D(3) (calcitriol), the activ...

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Publicat a:FEBS J
Autors principals: Fernández‐Barral, Asunción, Costales‐Carrera, Alba, Buira, Sandra P., Jung, Peter, Ferrer‐Mayorga, Gemma, Larriba, María Jesús, Bustamante‐Madrid, Pilar, Domínguez, Orlando, Real, Francisco X., Guerra‐Pastrián, Laura, Lafarga, Miguel, García‐Olmo, Damián, Cantero, Ramón, Del Peso, Luis, Batlle, Eduard, Rojo, Federico, Muñoz, Alberto, Barbáchano, Antonio
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Editor's Choice
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972655/
https://ncbi.nlm.nih.gov/pubmed/31306552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14998
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