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Novel endosomal NOX2 oxidase inhibitor ameliorates pandemic influenza A virus‐induced lung inflammation in mice

BACKGROUND AND OBJECTIVE: Influenza A viruses (IAV) cause respiratory tract infections that can be fatal when the virus spreads to the alveolar space (i.e. alveolitis), and this is mainly observed with highly pathogenic strains. Reactive oxygen species (ROS) production by the NOX2 NADPH oxidase in e...

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Dettagli Bibliografici
Pubblicato in:Respirology
Autori principali: To, Eunice E., Luong, Raymond, Diao, Jiayin, O’ Leary, John J., Brooks, Doug A., Vlahos, Ross, Selemidis, Stavros
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972593/
https://ncbi.nlm.nih.gov/pubmed/30884042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/resp.13524
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