NOX2 oxidase expressed in endosomes promotes cell proliferation and prostate tumour development

Reactive oxygen species (ROS) promote growth factor signalling including for VEGF-A and have potent angiogenic and tumourigenic properties. However, the precise enzymatic source of ROS generation, the subcellular localization of ROS production and cellular targets in vivo that influence tumour-promo...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Harrison, Ian P., Vinh, Antony, Johnson, Ian R.D., Luong, Raymond, Drummond, Grant R., Sobey, Christopher G., Tiganis, Tony, Williams, Elizabeth D., O’ Leary, John J., Brooks, Doug A., Selemidis, Stavros
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6226044/
https://ncbi.nlm.nih.gov/pubmed/30459931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26237
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