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Copper‐Catalyzed Triboration of Terminal Alkynes Using B(2)pin(2): Efficient Synthesis of 1,1,2‐Triborylalkenes

We report herein the catalytic triboration of terminal alkynes with B(2)pin(2) (bis(pinacolato)diboron) using readily available Cu(OAc)(2) and P(n)Bu(3). Various 1,1,2‐triborylalkenes, a class of compounds that have been demonstrated to be potential matrix metalloproteinase (MMP‐2) inhibitors, were...

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發表在:Angew Chem Int Ed Engl
Main Authors: Liu, Xiaocui, Ming, Wenbo, Friedrich, Alexandra, Kerner, Florian, Marder, Todd B.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972586/
https://ncbi.nlm.nih.gov/pubmed/31502712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201908466
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