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A first Japanese case of neuroendocrine prostate cancer accompanied by lung and brain metastasis with somatic and germline BRCA2 mutation

Germline mutations and copy number changes in DNA damage repair (DDR) genes such as BRCA2 are associated with aggressive forms of prostate cancer (PCa). Although the prevalence of BRCA2 variants in PCa is increasing in Japan, the genomic and biological implications in Japanese patients are unclear....

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Bibliografiske detaljer
Udgivet i:Pathol Int
Main Authors: Kosaka, Takeo, Hongo, Hiroshi, Aimono, Eriko, Matsumoto, Kazuhiro, Hayashida, Tetsu, Mikami, Shuji, Nishihara, Hiroshi, Oya, Mototsugu
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6972566/
https://ncbi.nlm.nih.gov/pubmed/31631483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pin.12860
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