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STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts

Induction of autophagy can have beneficial effects in several human diseases, e.g. cancer and neurodegenerative diseases (ND). Here, we therefore evaluated the potential of two novel autophagy-inducing compounds, i.e. STF-62247 and pimozide, to stimulate autophagy as well as autophagic cell death (A...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Kinzler, Maximilian N., Zielke, Svenja, Kardo, Simon, Meyer, Nina, Kögel, Donat, van Wijk, Sjoerd J. L., Fulda, Simone
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971264/
https://ncbi.nlm.nih.gov/pubmed/31959760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56990-y
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