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STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts

Induction of autophagy can have beneficial effects in several human diseases, e.g. cancer and neurodegenerative diseases (ND). Here, we therefore evaluated the potential of two novel autophagy-inducing compounds, i.e. STF-62247 and pimozide, to stimulate autophagy as well as autophagic cell death (A...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kinzler, Maximilian N., Zielke, Svenja, Kardo, Simon, Meyer, Nina, Kögel, Donat, van Wijk, Sjoerd J. L., Fulda, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971264/
https://ncbi.nlm.nih.gov/pubmed/31959760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-56990-y
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