Intercellular Adhesion Molecule-1 (ICAM-1) and ICAM-2 Differentially Contribute to Peripheral Activation and CNS Entry of Autoaggressive Th1 and Th17 Cells in Experimental Autoimmune Encephalomyelitis

In experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), myelin-specific T cells are activated in the periphery and differentiate in T helper (Th) 1 and Th17 effector cells, which cross the blood-brain barrier (BBB) to reach the central nervous system (CNS), wh...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: Haghayegh Jahromi, Neda, Marchetti, Luca, Moalli, Federica, Duc, Donovan, Basso, Camilla, Tardent, Heidi, Kaba, Elisa, Deutsch, Urban, Pot, Caroline, Sallusto, Federica, Stein, Jens V., Engelhardt, Britta
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970977/
https://ncbi.nlm.nih.gov/pubmed/31993059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03056
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