Sequential cocaine-alcohol self-administration produces adaptations in rat nucleus accumbens core glutamate homeostasis that are distinct from those produced by cocaine self-administration alone

There are currently no FDA-approved medications to reduce cocaine relapse. The majority of preclinical studies aimed at identifying the neurobiology underlying relapse involve the self-administration of cocaine alone, whereas many, if not a majority, of cocaine users engage in polysubstance use. Her...

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Veröffentlicht in:Neuropsychopharmacology
Hauptverfasser: Stennett, Bethany A., Padovan-Hernandez, Yasmin, Knackstedt, Lori A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969168/
https://ncbi.nlm.nih.gov/pubmed/31266052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0452-2
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