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Blocking CRH receptors in adults mitigates age-related memory impairments provoked by early-life adversity

In humans, early-life adversity is associated with impairments in learning and memory that may emerge later in life. In rodent models, early-life adversity directly impacts hippocampal neuron structure and connectivity with progressive deficits in long-term potentiation and spatial memory function....

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Библиографические подробности
Опубликовано в: :Neuropsychopharmacology
Главные авторы: Short, Annabel K., Maras, Pamela M., Pham, Aidan L., Ivy, Autumn S., Baram, Tallie Z.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer International Publishing 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969076/
https://ncbi.nlm.nih.gov/pubmed/31698409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0562-x
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