Hippocampal Dysfunction and Cognitive Impairments Provoked by Chronic Early-Life Stress Involve Excessive Activation of CRH Receptors

Chronic stress impairs learning and memory in humans and rodents and disrupts long-term potentiation (LTP) in animal models. These effects are associated with structural changes in hippocampal neurons, including reduced dendritic arborization. Unlike the generally reversible effects of chronic stres...

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Hlavní autoři: Ivy, Autumn S., Rex, Christopher S., Chen, Yuncai, Dubé, Céline, Maras, Pamela M., Grigoriadis, Dimitri E., Gall, Christine M., Lynch, Gary, Baram, Tallie Z.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991143/
https://ncbi.nlm.nih.gov/pubmed/20881118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1784-10.2010
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