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Dexmedetomidine alleviates insulin resistance in hepatocytes by reducing endoplasmic reticulum stress

PURPOSE: Dexmedetomidine (DEX) stabilizes intraoperative blood glucose levels and reduces insulin resistance (IR), a common perioperative complication. However, the molecular mechanisms underlying these effects remain unclear. Since endoplasmic reticulum stress (ERS) is a mechanism of IR, this study...

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Publicat a:Endocrine
Autors principals: Liu, Fanfan, Zhu, Shaojun, Ni, Lifeng, Huang, Ling’er, Wang, Kuirong, Zhou, Yanfeng
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969002/
https://ncbi.nlm.nih.gov/pubmed/31679138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12020-019-02118-1
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