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Synthesis, antibacterial and anticancer activity, and docking study of aminoguanidines containing an alkynyl moiety

Two series of aminoguanidines containing an alkynyl moiety were designed, synthesised, and screened for antibacterial and anticancer activities. Generally, the series 3a–3j with a 1,2-diphenylethyne exhibited better antibacterial activity than the other series (6a–6k) holding 1,4-diphenylbuta-1,3-di...

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Detalles Bibliográficos
Publicado en:J Enzyme Inhib Med Chem
Main Authors: Deng, Xianqing, Song, Mingxia
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6968633/
https://ncbi.nlm.nih.gov/pubmed/31851531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1702654
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