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Synthesis, antibacterial and anticancer activity, and docking study of aminoguanidines containing an alkynyl moiety

Two series of aminoguanidines containing an alkynyl moiety were designed, synthesised, and screened for antibacterial and anticancer activities. Generally, the series 3a–3j with a 1,2-diphenylethyne exhibited better antibacterial activity than the other series (6a–6k) holding 1,4-diphenylbuta-1,3-di...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Deng, Xianqing, Song, Mingxia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6968633/
https://ncbi.nlm.nih.gov/pubmed/31851531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1702654
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