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A novel function of AAA-ATPase p97/VCP in the regulation of cell motility

High level of the multifunctional AAA-ATPase p97/VCP is often correlated to the development of cancer; however, the underlying mechanism is not understood completely. Here, we report a novel function of p97/VCP in actin regulation and cell motility. We found that loss of p97/VCP promotes stabilizati...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Khong, Zi-Jia, Lai, Soak-Kuan, Koh, Cheng-Gee, Geifman-Shochat, Susana, Li, Hoi-Yeung
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6967774/
https://ncbi.nlm.nih.gov/pubmed/32002125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27419
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