Pharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine

PURPOSE: Pharmacogenes have an influence on biotransformation pathway and clinical outcome of primaquine and chloroquine which are often prescribed to treat Plasmodium vivax infection. Genetic variation may impact enzyme activity and/or transporter function and thereby contribute to relapse. The aim...

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Detalhes bibliográficos
Publicado no:Pharmgenomics Pers Med
Main Authors: Chamnanphon, Monpat, Gaedigk, Andrea, Puangpetch, Apichaya, Pasomsub, Ekawat, Chantratita, Wasun, Longley, Rhea J, Sattabongkot, Jetsumon, Chariyavilaskul, Pajaree, Sukasem, Chonlaphat
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966953/
https://ncbi.nlm.nih.gov/pubmed/32021383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S201007
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