∆Np63/p40 correlates with the location and phenotype of basal/mesenchymal cancer stem‐like cells in human ER(+) and HER2(+) breast cancers

ΔNp63, also known as p40, regulates stemness of normal mammary gland epithelium and provides stem cell characteristics in basal and HER2‐driven murine breast cancer models. Whilst ΔNp63/p40 is a characteristic feature of normal basal cells and basal‐type triple‐negative breast cancer, some receptor‐...

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Vydáno v:J Pathol Clin Res
Hlavní autoři: Liu, Yajing, Nekulova, Marta, Nenutil, Rudolf, Horakova, Iva, Appleyard, M Virginia, Murray, Karen, Holcakova, Jitka, Galoczova, Michaela, Quinlan, Philip, Jordan, Lee B, Purdie, Colin A, Vojtesek, Borivoj, Thompson, Alastair M, Coates, Philip J
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2019
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966710/
https://ncbi.nlm.nih.gov/pubmed/31591823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.149
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