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Changes of O(6)-Methylguanine DNA Methyltransferase (MGMT) Promoter Methylation in Glioblastoma Relapse—A Meta-Analysis Type Literature Review

Methylation of the O(6)-methylguanine DNA methyltransferase (MGMT) promoter has emerged as strong prognostic factor in the therapy of glioblastoma multiforme. It is associated with an improved response to chemotherapy with temozolomide and longer overall survival. MGMT promoter methylation has impli...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Feldheim, Jonas, Kessler, Almuth F., Monoranu, Camelia M., Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966671/
https://ncbi.nlm.nih.gov/pubmed/31766430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121837
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