Changes of O(6)-Methylguanine DNA Methyltransferase (MGMT) Promoter Methylation in Glioblastoma Relapse—A Meta-Analysis Type Literature Review

Methylation of the O(6)-methylguanine DNA methyltransferase (MGMT) promoter has emerged as strong prognostic factor in the therapy of glioblastoma multiforme. It is associated with an improved response to chemotherapy with temozolomide and longer overall survival. MGMT promoter methylation has impli...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Feldheim, Jonas, Kessler, Almuth F., Monoranu, Camelia M., Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966671/
https://ncbi.nlm.nih.gov/pubmed/31766430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121837
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