Expression of activating transcription factor 5 (ATF5) is increased in astrocytomas of different WHO grades and correlates with survival of glioblastoma patients

BACKGROUND: ATF5 suppresses differentiation of neuroprogenitor cells and is overexpressed in glioblastoma (GBM). A reduction of its expression leads to apoptotic GBM cell death. Data on ATF5 expression in astrocytoma WHO grade II (low-grade astrocytoma [LGA]) are scarce and lacking on recurrent GBM....

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Feldheim, Jonas, Kessler, Almuth F, Schmitt, Dominik, Wilczek, Lara, Linsenmann, Thomas, Dahlmann, Mathias, Monoranu, Camelia M, Ernestus, Ralf-Ingo, Hagemann, Carsten, Löhr, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6287669/
https://ncbi.nlm.nih.gov/pubmed/30584325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S176549
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