Direct Targeting Options for STAT3 and STAT5 in Cancer

Signal transducer and activator of transcription (STAT)3 and STAT5 are important transcription factors that are able to mediate or even drive cancer progression through hyperactivation or gain-of-function mutations. Mutated STAT3 is mainly associated with large granular lymphocytic T-cell leukemia,...

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Podrobná bibliografie
Vydáno v:Cancers (Basel)
Hlavní autoři: Orlova, Anna, Wagner, Christina, de Araujo, Elvin D., Bajusz, Dávid, Neubauer, Heidi A., Herling, Marco, Gunning, Patrick T., Keserű, György M., Moriggl, Richard
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966570/
https://ncbi.nlm.nih.gov/pubmed/31817042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121930
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