The Expression of Myeloproliferative Neoplasm-Associated Calreticulin Variants Depends on the Functionality of ER-Associated Degradation

Background: Mutations in CALR observed in myeloproliferative neoplasms (MPN) were recently shown to be pathogenic via their interaction with MPL and the subsequent activation of the Janus Kinase – Signal Transducer and Activator of Transcription (JAK-STAT) pathway. However, little is known on the im...

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Publicado no:Cancers (Basel)
Main Authors: Mansier, Olivier, Prouzet-Mauléon, Valérie, Jégou, Gwénaële, Barroso, Kim, Raymundo, Diana Pelizzari, Chauveau, Aurélie, Dumas, Pierre-Yves, Lagarde, Valérie, Turcq, Béatrice, Pasquet, Jean-Max, Viallard, Jean-François, James, Chloé, Praloran, Vincent, Voutetakis, Konstantinos, Chatziioannou, Aristotelis, Mahon, François-Xavier, Chevet, Eric, Lippert, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966542/
https://ncbi.nlm.nih.gov/pubmed/31810292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121921
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