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Elevated Autotaxin and LPA Levels during Chronic Viral Hepatitis and Hepatocellular Carcinoma Associate with Systemic Immune Activation

Circulating autotaxin (ATX) is elevated in persons with liver disease, particularly in the setting of chronic hepatitis C virus (HCV) and HCV/HIV infection. It is thought that plasma ATX levels are, in part, attributable to impaired liver clearance that is secondary to fibrotic liver disease. In a d...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Kostadinova, Lenche, Shive, Carey L, Anthony, Donald D
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966516/
https://ncbi.nlm.nih.gov/pubmed/31769428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121867
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