The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation

The deregulation of the Wnt/β-catenin signaling pathway is a central event in colorectal cancer progression, thus a promising target for drug development. Many natural compounds, such as flavonoids, have been described as Wnt/β-catenin inhibitors and consequently modulate important biological proces...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Predes, Danilo, Oliveira, Luiz F. S., Ferreira, Laís S. S., Maia, Lorena A., Delou, João M. A., Faletti, Anderson, Oliveira, Igor, Amado, Nathalia G., Reis, Alice H., Fraga, Carlos A. M., Kuster, Ricardo, Mendes, Fabio A., Borges, Helena L., Abreu, Jose G.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966512/
https://ncbi.nlm.nih.gov/pubmed/31817828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121968
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