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Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells
More than 94% of colorectal cancer cases have mutations in one or more Wnt/β-catenin signaling pathway components. Inactivating mutations in APC or activating mutations in β-catenin (CTNNB1) lead to signaling overactivation and subsequent intestinal hyperplasia. Numerous classes of medicines derived...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7363889/ https://ncbi.nlm.nih.gov/pubmed/32669593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68574-2 |
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