Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer

Advanced prostate cancer is a very heterogeneous disease reflecting in diverse regulations of oncogenic signaling pathways. Aberrant spatial dynamics of epidermal growth factor receptor (EGFR) promote their dimerization and clustering, leading to constitutive activation in oncogenesis. The EphB2 and...

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Bibliografische gegevens
Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Liu, Yen-Liang, Horning, Aaron M., Lieberman, Brandon, Kim, Mirae, Lin, Che-Kuang, Hung, Chia-Nung, Chou, Chih-Wei, Wang, Chiou-Miin, Lin, Chun-Lin, Kirma, Nameer B., Liss, Michael A., Vasisht, Rohan, Perillo, Evan P., Blocher, Katherine, Horng, Hannah, Taverna, Josephine A., Ruan, Jianhua, Yankeelov, Thomas E., Dunn, Andrew K., Huang, Tim H.-M., Yeh, Hsin-Chih, Chen, Chun-Liang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966510/
https://ncbi.nlm.nih.gov/pubmed/31805710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121910
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