Leptin induces partial epithelial-mesenchymal transition in a FAK-ERK dependent pathway in MCF10A mammary non-tumorigenic cells

Epithelial-mesenchymal transition (EMT) is a biological process involved in different steps of tumor progression and metastasis of breast cancer cells. Epidemiological studies suggest a link between obesity and the progression of breast cancer. Leptin is an adipocyte-secreted hormone which can promo...

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Veröffentlicht in:Int J Clin Exp Pathol
Hauptverfasser: Villanueva-Duque, Alfredo, Zuniga-Eulogio, Miriam Daniela, Dena-Beltran, Jose, Castaneda-Saucedo, Eduardo, Calixto-Galvez, Mercedes, Mendoza-Catalán, Miguel Angel, Ortuno-Pineda, Carlos, Navarro-Tito, Napoleon
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965759/
https://ncbi.nlm.nih.gov/pubmed/31966368
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