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A model for gain of function in superoxide dismutase
Studies have found that mutant, misfolded superoxide dismutase [Cu–Zn] (SOD1) can convert wild type SOD1 (wtSOD1) in a prion-like fashion, and that misfolded wtSOD1 can be propagated by release and uptake of protein aggregates. In developing a prion-like mechanism for this propagation of SOD1 misfol...
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| Опубликовано в: : | Biochem Biophys Rep |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6965706/ https://ncbi.nlm.nih.gov/pubmed/31970293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100728 |
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