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Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts

BACKGROUND AND PURPOSE: The intracellular signalling molecule cGMP, formed by NO‐sensitive GC (NO–GC), has an established function in the vascular system. Despite numerous reports about NO‐induced cGMP effects in the heart, the underlying cGMP signals are poorly characterized. EXPERIMENTAL APPROACH:...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Menges, Lukas, Krawutschke, Christian, Füchtbauer, Ernst‐Martin, Füchtbauer, Annette, Sandner, Peter, Koesling, Doris, Russwurm, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965686/
https://ncbi.nlm.nih.gov/pubmed/31423565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14835
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