Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts

BACKGROUND AND PURPOSE: The intracellular signalling molecule cGMP, formed by NO‐sensitive GC (NO–GC), has an established function in the vascular system. Despite numerous reports about NO‐induced cGMP effects in the heart, the underlying cGMP signals are poorly characterized. EXPERIMENTAL APPROACH:...

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Publicado en:Br J Pharmacol
Autores principales: Menges, Lukas, Krawutschke, Christian, Füchtbauer, Ernst‐Martin, Füchtbauer, Annette, Sandner, Peter, Koesling, Doris, Russwurm, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965686/
https://ncbi.nlm.nih.gov/pubmed/31423565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14835
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