Mind the gap (junction): cGMP induced by nitric oxide in cardiac myocytes originates from cardiac fibroblasts

BACKGROUND AND PURPOSE: The intracellular signalling molecule cGMP, formed by NO‐sensitive GC (NO–GC), has an established function in the vascular system. Despite numerous reports about NO‐induced cGMP effects in the heart, the underlying cGMP signals are poorly characterized. EXPERIMENTAL APPROACH:...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Menges, Lukas, Krawutschke, Christian, Füchtbauer, Ernst‐Martin, Füchtbauer, Annette, Sandner, Peter, Koesling, Doris, Russwurm, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965686/
https://ncbi.nlm.nih.gov/pubmed/31423565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14835
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