ADT-OH, a hydrogen sulfide-releasing donor, induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD

Hydrogen sulfide (H(2)S) is now widely considered the third endogenous gasotransmitter and plays critical roles in cancer biological processes. In this study, we demonstrate that 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (ADT-OH), the most widely used moiety for synthesising slow-releasing H(2)S...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Cai, Fangfang, Xu, Huangru, Cao, Nini, Zhang, Xiangyu, Liu, Jia, Lu, Yanyan, Chen, Jia, Yang, Yunwen, Cheng, Jian, Hua, Zi-Chun, Zhuang, Hongqin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965651/
https://ncbi.nlm.nih.gov/pubmed/31949127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2222-9
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