High Frequency Production of T Cell-Derived iPSC Clones Capable of Generating Potent Cytotoxic T Cells

Current adoptive T cell therapies conducted in an autologous setting are costly, time-consuming, and depend on the quality of the patient’s T cells, and thus it would be highly beneficial to develop an allogeneic strategy. To this aim, we have developed a method by which cytotoxic T lymphocytes (CTL...

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Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Nagano, Seiji, Maeda, Takuya, Ichise, Hiroshi, Kashima, Soki, Ohtaka, Manami, Nakanishi, Mahito, Kitawaki, Toshio, Kadowaki, Norimitsu, Takaori-Kondo, Akifumi, Masuda, Kyoko, Kawamoto, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965501/
https://ncbi.nlm.nih.gov/pubmed/31970197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.12.006
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