An assessment of the effects of ectopic gp91phox expression in XCGD iPSC-derived neutrophils

For the treatment of monogenetic hematological disorders, restoration of transgene expression in affected cell populations is generally considered to have beneficial effects. However, X-linked chronic granulomatous disease (XCGD) is unique since the appearance of functional neutrophils in the periph...

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Pubblicato in:Mol Ther Methods Clin Dev
Autori principali: Lin, Huan-Ting, Masaki, Hideki, Yamaguchi, Tomoyuki, Wada, Taizo, Yachie, Akihiro, Nishimura, Ken, Ohtaka, Manami, Nakanishi, Mahito, Nakauchi, Hiromitsu, Otsu, Makoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674005/
https://ncbi.nlm.nih.gov/pubmed/26682238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.46
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