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Obeticholic acid improves hepatic steatosis and inflammation by inhibiting NLRP3 inflammasome activation

Background and Aim: Several pre-clinical and clinical researches have proved that obeticholic acid (OCA)has a potential therapeutic effect on non-alcoholic steatohepatitis (NASH). Our aim was to investigate whether the therapeutic effect of OCA on NASH was attributed to its inhibition effect on cyto...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Yang, Zhi-Yu, Liu, Feng, Liu, Pei-Hao, Guo, Wan-Jun, Xiong, Guo-Yu, Pan, Hai, Wei, Lai
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965461/
https://ncbi.nlm.nih.gov/pubmed/31966664
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