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The impact of adjusting for baseline in pharmacogenomic genome-wide association studies of quantitative change

In pharmacogenomic studies of quantitative change, any association between genetic variants and the pretreatment (baseline) measurement can bias the estimate of effect between those variants and drug response. A putative solution is to adjust for baseline. We conducted a series of genome-wide associ...

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Podrobná bibliografie
Vydáno v:NPJ Genom Med
Hlavní autoři: Oni-Orisan, Akinyemi, Haldar, Tanushree, Ranatunga, Dilrini K., Medina, Marisa W., Schaefer, Catherine, Krauss, Ronald M., Iribarren, Carlos, Risch, Neil, Hoffmann, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965183/
https://ncbi.nlm.nih.gov/pubmed/31969989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-019-0109-4
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