Targeting Forward and Reverse EphB4/EFNB2 Signaling by a Peptide with Dual Functions

The tyrosine kinase receptor EphB4 is frequently overexpressed in ovarian and other solid tumors and is involved in interactions between tumor cells and the tumor microenvironment, contributing to metastasis. Trans-interaction between EphB4 and its membrane-bound ligand ephrin B2 (EFNB2) mediates bi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xiong, Chiyi, Wen, Yunfei, Zhao, Jun, Yin, Dengke, Xu, Lingyun, Chelariu-Raicu, Anca, Yao, Cody, Leng, Xiaohong, Liu, Jinsong, Chaudhari, Rajan R., Zhang, Shuxing, Sood, Anil K., Li, Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965176/
https://ncbi.nlm.nih.gov/pubmed/31949258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57477-x
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