Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

A comprehensive characterization of the lipidome from limited starting material remains very challenging. Here we report a high-sensitivity lipidomics workflow based on nanoflow liquid chromatography and trapped ion mobility spectrometry (TIMS). Taking advantage of parallel accumulation–serial fragm...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Vasilopoulou, Catherine G., Sulek, Karolina, Brunner, Andreas-David, Meitei, Ningombam Sanjib, Schweiger-Hufnagel, Ulrike, Meyer, Sven W., Barsch, Aiko, Mann, Matthias, Meier, Florian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965134/
https://ncbi.nlm.nih.gov/pubmed/31949144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14044-x
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