Online Parallel Accumulation–Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer

In bottom-up proteomics, peptides are separated by liquid chromatography with elution peak widths in the range of seconds, whereas mass spectra are acquired in about 100 microseconds with time-of-flight (TOF) instruments. This allows adding ion mobility as a third dimension of separation. Among seve...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Meier, Florian, Brunner, Andreas-David, Koch, Scarlet, Koch, Heiner, Lubeck, Markus, Krause, Michael, Goedecke, Niels, Decker, Jens, Kosinski, Thomas, Park, Melvin A., Bache, Nicolai, Hoerning, Ole, Cox, Jürgen, Räther, Oliver, Mann, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Technological Innovation Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6283298/
https://ncbi.nlm.nih.gov/pubmed/30385480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR118.000900
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