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The matrix vesicle cargo miR-125b accumulates in the bone matrix, inhibiting bone resorption in mice
Communication between osteoblasts and osteoclasts plays a key role in bone metabolism. We describe here an unexpected role for matrix vesicles (MVs), which bud from bone-forming osteoblasts and have a well-established role in initiation of bone mineralization, in osteoclastogenesis. We show that the...
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| Publicado en: | Commun Biol |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6965124/ https://ncbi.nlm.nih.gov/pubmed/31949279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0754-2 |
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