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M1 macrophage dependent-p53 regulates the intracellular survival of mycobacteria

Tumor suppressor p53 is not only affects immune responses but also contributes to antibacterial activity. However, its bactericidal function during mycobacterial infection remains unclear. In this study, we found that the p53-deficient macrophages failed to control Mycobacterium tuberculosis (Mtb),...

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Bibliografische gegevens
Gepubliceerd in:Apoptosis
Hoofdauteurs: Lim, Yun-Ji, Lee, Junghwan, Choi, Ji-Ae, Cho, Soo-Na, Son, Sang-Hun, Kwon, Sun-Jung, Son, Ji-Woong, Song, Chang-Hwa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965052/
https://ncbi.nlm.nih.gov/pubmed/31691131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-019-01578-0
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