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M1 macrophage dependent-p53 regulates the intracellular survival of mycobacteria

Tumor suppressor p53 is not only affects immune responses but also contributes to antibacterial activity. However, its bactericidal function during mycobacterial infection remains unclear. In this study, we found that the p53-deficient macrophages failed to control Mycobacterium tuberculosis (Mtb),...

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Bibliographic Details
Published in:Apoptosis
Main Authors: Lim, Yun-Ji, Lee, Junghwan, Choi, Ji-Ae, Cho, Soo-Na, Son, Sang-Hun, Kwon, Sun-Jung, Son, Ji-Woong, Song, Chang-Hwa
Format: Artigo
Language:Inglês
Published: Springer US 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965052/
https://ncbi.nlm.nih.gov/pubmed/31691131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-019-01578-0
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