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M1 macrophage dependent-p53 regulates the intracellular survival of mycobacteria

Tumor suppressor p53 is not only affects immune responses but also contributes to antibacterial activity. However, its bactericidal function during mycobacterial infection remains unclear. In this study, we found that the p53-deficient macrophages failed to control Mycobacterium tuberculosis (Mtb),...

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Detalhes bibliográficos
Publicado no:Apoptosis
Main Authors: Lim, Yun-Ji, Lee, Junghwan, Choi, Ji-Ae, Cho, Soo-Na, Son, Sang-Hun, Kwon, Sun-Jung, Son, Ji-Woong, Song, Chang-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965052/
https://ncbi.nlm.nih.gov/pubmed/31691131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-019-01578-0
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