Clinico-neuropathological features of isocitrate dehydrogenase 2 gene mutations in lower-grade gliomas

BACKGROUND: Mutations in the isocitrate dehydrogenase 1 (IDH1) and IDH2 genes are important for both the integrated diagnosis and the prognosis of diffuse gliomas. The p.R132H mutation of IDH1 is the most frequently observed IDH mutation, while IDH2 mutations were relatively rarely studied. The aim...

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Enregistré dans:
Détails bibliographiques
Publié dans:Chin Med J (Engl)
Auteurs principaux: Wang, Lei-Ming, Li, Zhuo, Piao, Yue-Shan, Cai, Yan-Ning, Zhang, Li-Yan, Ge, Hai-Jing, Xu, Wei-Wei, Lu, De-Hong
Format: Artigo
Langue:Inglês
Publié: Wolters Kluwer Health 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964951/
https://ncbi.nlm.nih.gov/pubmed/31833906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CM9.0000000000000565
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