Clinico-neuropathological features of isocitrate dehydrogenase 2 gene mutations in lower-grade gliomas

BACKGROUND: Mutations in the isocitrate dehydrogenase 1 (IDH1) and IDH2 genes are important for both the integrated diagnosis and the prognosis of diffuse gliomas. The p.R132H mutation of IDH1 is the most frequently observed IDH mutation, while IDH2 mutations were relatively rarely studied. The aim...

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Bibliografske podrobnosti
izdano v:Chin Med J (Engl)
Main Authors: Wang, Lei-Ming, Li, Zhuo, Piao, Yue-Shan, Cai, Yan-Ning, Zhang, Li-Yan, Ge, Hai-Jing, Xu, Wei-Wei, Lu, De-Hong
Format: Artigo
Jezik:Inglês
Izdano: Wolters Kluwer Health 2019
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964951/
https://ncbi.nlm.nih.gov/pubmed/31833906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CM9.0000000000000565
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