SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning–specific memory traces

Neurons store information by changing synaptic input weights. In addition, they can adjust their membrane excitability to alter spike output. Here, we demonstrate a role of such “intrinsic plasticity” in behavioral learning in a mouse model that allows us to detect specific consequences of absent ex...

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Bibliografiske detaljer
Udgivet i:PLoS Biol
Main Authors: Grasselli, Giorgio, Boele, Henk-Jan, Titley, Heather K., Bradford, Nora, van Beers, Lisa, Jay, Lindsey, Beekhof, Gerco C., Busch, Silas E., De Zeeuw, Chris I., Schonewille, Martijn, Hansel, Christian
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964916/
https://ncbi.nlm.nih.gov/pubmed/31905212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000596
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