Cerebellar and Extracerebellar Involvement in Mouse Eyeblink Conditioning: the ACDC Model

by Boele, Henk-Jan, Koekkoek, Sebastiaan K. E., De Zeeuw, Chris I.
Published 2010

High Frequency Burst Firing of Granule Cells Ensures Transmission at the Parallel Fiber to Purkinje Cell Synapse at the Cost of Temporal Coding

by van Beugen, Boeke J., Gao, Zhenyu, Boele, Henk-Jan, Hoebeek, Freek, De Zeeuw, Chris I.
Published 2013

Axonal Sprouting and Formation of Terminals in the Adult Cerebellum during Associative Motor Learning

by Boele, Henk-Jan, Koekkoek, Sebastiaan K. E., De Zeeuw, Chris I., Ruigrok, Tom J. H.
Published in J Neurosci (2013)

Performance in eyeblink conditioning is age and sex dependent

by Löwgren, Karolina, Bååth, Rasmus, Rasmussen, Anders, Boele, Henk-Jan, Koekkoek, Sebastiaan K. E., De Zeeuw, Chris I., Hesslow, Germund
Published in PLoS One (2017)

Young Domestic Pigs (Sus scrofa) Can Perform Pavlovian Eyeblink Conditioning

by Boele, Henk-Jan, Joung, Sangyun, Fil, Joanne E., Mudd, Austin T., Fleming, Stephen A., Koekkoek, Sebastiaan K. E., Dilger, Ryan N.
Published in Front Behav Neurosci (2021)

Spinocerebellar Ataxia Type 6 Protein Aggregates Cause Deficits in Motor Learning and Cerebellar Plasticity

by Mark, Melanie D., Krause, Martin, Boele, Henk-Jan, Kruse, Wolfgang, Pollok, Stefan, Kuner, Thomas, Dalkara, Deniz, Koekkoek, Sebastiaan, De Zeeuw, Chris I., Herlitze, Stefan
Published in J Neurosci (2015)

Dynamic modulation of activity in cerebellar nuclei neurons during pavlovian eyeblink conditioning in mice

by ten Brinke, Michiel M, Heiney, Shane A, Wang, Xiaolu, Proietti-Onori, Martina, Boele, Henk-Jan, Bakermans, Jacob, Medina, Javier F, Gao, Zhenyu, De Zeeuw, Chris I
Published in eLife (2017)

Impact of parallel fiber to Purkinje cell long-term depression is unmasked in absence of inhibitory input

by Boele, Henk-Jan, Peter, Saša, Ten Brinke, Michiel M., Verdonschot, Lucas, IJpelaar, Anna C. H., Rizopoulos, Dimitris, Gao, Zhenyu, Koekkoek, Sebastiaan K. E., De Zeeuw, Chris I.
Published in Sci Adv (2018)

Excitatory Cerebellar Nucleocortical Circuit Provides Internal Amplification during Associative Conditioning

by Gao, Zhenyu, Proietti-Onori, Martina, Lin, Zhanmin, ten Brinke, Michiel M., Boele, Henk-Jan, Potters, Jan-Willem, Ruigrok, Tom J.H., Hoebeek, Freek E., De Zeeuw, Chris I.
Published in Neuron (2016)

Impaired Spatio-Temporal Predictive Motor Timing Associated with Spinocerebellar Ataxia Type 6

by Broersen, Robin, Onuki, Yoshiyuki, Abdelgabar, Abdel R., Owens, Cullen B., Picard, Samuel, Willems, Jessica, Boele, Henk-Jan, Gazzola, Valeria, Van der Werf, Ysbrand D., De Zeeuw, Chris I.
Published in PLoS One (2016)

TRPC3 is a major contributor to functional heterogeneity of cerebellar Purkinje cells

by Wu, Bin, Blot, François GC, Wong, Aaron Benson, Osório, Catarina, Adolfs, Youri, Pasterkamp, R Jeroen, Hartmann, Jana, Becker, Esther BE, Boele, Henk-Jan, De Zeeuw, Chris I, Schonewille, Martijn
Published in eLife (2019)

Cerebellar Cortex and Cerebellar Nuclei Are Concomitantly Activated during Eyeblink Conditioning: A 7T fMRI Study in Humans

by Thürling, Markus, Kahl, Fabian, Maderwald, Stefan, Stefanescu, Roxana M., Schlamann, Marc, Boele, Henk-Jan, De Zeeuw, Chris I., Diedrichsen, Jörn, Ladd, Mark E., Koekkoek, Sebastiaan K. E., Timmann, Dagmar
Published in J Neurosci (2015)

SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning–specific memory traces

by Grasselli, Giorgio, Boele, Henk-Jan, Titley, Heather K., Bradford, Nora, van Beers, Lisa, Jay, Lindsey, Beekhof, Gerco C., Busch, Silas E., De Zeeuw, Chris I., Schonewille, Martijn, Hansel, Christian
Published in PLoS Biol (2020)

Evolving Models of Pavlovian Conditioning: Cerebellar Cortical Dynamics in Awake Behaving Mice

by ten Brinke, Michiel M., Boele, Henk-Jan, Spanke, Jochen K., Potters, Jan-Willem, Kornysheva, Katja, Wulff, Peer, IJpelaar, Anna C.H.G., Koekkoek, Sebastiaan K.E., De Zeeuw, Chris I.
Published in Cell Rep (2015)

Cerebellar plasticity and associative memories are controlled by perineuronal nets

by Carulli, Daniela, Broersen, Robin, de Winter, Fred, Muir, Elizabeth M., Mešković, Maja, de Waal, Matthijs, de Vries, Sharon, Boele, Henk-Jan, Canto, Cathrin B., De Zeeuw, Chris I., Verhaagen, Joost
Published in Proc Natl Acad Sci U S A (2020)

Modulation of 7 T fMRI Signal in the Cerebellar Cortex and Nuclei During Acquisition, Extinction, and Reacquisition of Conditioned Eyeblink Responses

by Ernst, Thomas M., Thürling, Markus, Müller, Sarah, Kahl, Fabian, Maderwald, Stefan, Schlamann, Marc, Boele, Henk‐Jan, Koekkoek, Sebastiaan K. E., Diedrichsen, Jörn, De Zeeuw, Chris I., Ladd, Mark E., Timmann, Dagmar
Published in Hum Brain Mapp (2017)

AMPAR Auxiliary Protein SHISA6 Facilitates Purkinje Cell Synaptic Excitability and Procedural Memory Formation

by Peter, Saša, Urbanus, Bastiaan H.A., Klaassen, Remco V., Wu, Bin, Boele, Henk-Jan, Azizi, Sameha, Slotman, Johan A., Houtsmuller, Adriaan B., Schonewille, Martijn, Hoebeek, Freek E., Spijker, Sabine, Smit, August B., De Zeeuw, Chris I.
Published in Cell Rep (2013)

Differential spatiotemporal development of Purkinje cell populations and cerebellum-dependent sensorimotor behaviors

by Beekhof, Gerrit Cornelis, Osório, Catarina, White, Joshua J, van Zoomeren, Scott, van der Stok, Hannah, Xiong, Bilian, Nettersheim, Ingo HMS, Mak, Willem Ashwin, Runge, Marit, Fiocchi, Francesca Romana, Boele, Henk-Jan, Hoebeek, Freek E, Schonewille, Martijn
Published in eLife (2021)

Reevaluating the Role of LTD in Cerebellar Motor Learning

by Schonewille, Martijn, Gao, Zhenyu, Boele, Henk-Jan, Veloz, Maria F. Vinueza, Amerika, Wardell E., Simek, Antonia A.M., De Jeu, Marcel T., Steinberg, Jordan P., Takamiya, Kogo, Hoebeek, Freek E., Linden, David J., Huganir, Richard L., De Zeeuw, Chris I.
Published 2011

Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice

by Peter, Saša, ten Brinke, Michiel M., Stedehouder, Jeffrey, Reinelt, Claudia M., Wu, Bin, Zhou, Haibo, Zhou, Kuikui, Boele, Henk-Jan, Kushner, Steven A., Lee, Min Goo, Schmeisser, Michael J., Boeckers, Tobias M., Schonewille, Martijn, Hoebeek, Freek E., De Zeeuw, Chris I.
Published in Nat Commun (2016)