Suppression of Superoxide-Hydrogen Peroxide Production at Site I(Q) of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes

Cardiogenic shock following cardiopulmonary resuscitation for sudden cardiac arrest is common, occurring even in the absence of acute coronary artery occlusion, and contributes to high rates of postcardiopulmonary resuscitation mortality. The pathophysiology of this shock is unclear, and effective t...

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Detalhes bibliográficos
Publicado no:Crit Care Med
Principais autores: Piao, Lin, Fang, Yong-Hu, Hamanaka, Robert B., Mutlu, Gökhan M., Dezfulian, Cameron, Archer, Stephen L., Sharp, Willard W.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2020
Assuntos:
Online Laboratory Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964871/
https://ncbi.nlm.nih.gov/pubmed/31939812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000004095
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