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ASCT2 (SLC1A5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma

BACKGROUND: Glutamine is an abundant and versatile nutrient in cancer cells. Head and neck squamous cell carcinoma (HNSCC) was reported to be dependent on mainly glucose, not glutamine, for producing the energy required for survival and proliferation. METHODS: The roles of ASCT2 (SLC1A5) and associa...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Zhang, Ze, Liu, Ruoyan, Shuai, Yanjie, Huang, Yuting, Jin, Rui, Wang, Xudong, Luo, Jingtao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964701/
https://ncbi.nlm.nih.gov/pubmed/31819178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0637-9
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