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A benchmark of batch-effect correction methods for single-cell RNA sequencing data

BACKGROUND: Large-scale single-cell transcriptomic datasets generated using different technologies contain batch-specific systematic variations that present a challenge to batch-effect removal and data integration. With continued growth expected in scRNA-seq data, achieving effective batch integrati...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Tran, Hoa Thi Nhu, Ang, Kok Siong, Chevrier, Marion, Zhang, Xiaomeng, Lee, Nicole Yee Shin, Goh, Michelle, Chen, Jinmiao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964114/
https://ncbi.nlm.nih.gov/pubmed/31948481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-019-1850-9
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