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Flexible experimental designs for valid single-cell RNA-sequencing experiments allowing batch effects correction

Despite their widespread applications, single-cell RNA-sequencing (scRNA-seq) experiments are still plagued by batch effects and dropout events. Although the completely randomized experimental design has frequently been advocated to control for batch effects, it is rarely implemented in real applica...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Song, Fangda, Chan, Ga Ming Angus, Wei, Yingying
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330047/
https://ncbi.nlm.nih.gov/pubmed/32612268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16905-2
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